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Buy Mifeprex Online | RU486 cost and efficacy

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Purchase Abortion pills Mifeprex – Mifepristone & Misoprostol Pills

Buy pills for Medical Termination of Pregnancy. Best quality RU486 is a complete abortion kit, which includes 1 pill of Mifepristone 200 mg, and 4 pills of Misoprostol 200 mg.

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Abortion pills Buy Mifeprex or RU486 United Kingdom – Working Mechanism, How to use ?

Buy Mifeprex or RU 486 Abortion Kit now available in Britain and Europe best works by blocking the progesterone action and breaking the uterus lining and placenta resulting in normal menstrual cycle and regular bleeding. Also, the drug opens the cervix, leading to contractions that help dislocate and expel the embryo.

Pills are available in Europe and West London with fast shipping and discreet packaging.

Abortion pills Mifeprex or RU 486 United Kingdom – Dosage Format

The pills of RU 486 should be taken only up to the first 9 weeks (or 75 days) of pregnancy (from the start of her last menstrual cycle).

Mifeprex or RU 486 Pills comes under the names: Cipla MTP kit, MifeGymiso, Mifeprex, Mifegyne and Mifepristone.

Mifepre or RU 486 medication is accompanied with Misoprostol in the dosage formats as given below under a proper medical supervision :-

  •  In the first step, visit a clinic or a medical expert to discuss one’s medical history and take the pregnancy test.
  •  Next, take the RU 486 tablet orally – 3 pills of 200 mg each with a glass of water.
  •  After 48 hours of RU 486 consumption, take the 2 prostaglandin (Misoprostol) tablets to complete the abortion process, you can complete this abortion process at home and have complete privacy.
  • Post some days or 1-2 weeks, return to the clinic to check for complete abortion (complete termination of pregnancy)

 

Abortion pills Mifeprex or RU486  United Kingdom –  Precautions

RU486 must not be used with any other contradictory medicines that can create any kind of contradictions, so it is advisable to consult a medical specialist to discuss one’s medical history before using RU-486 for medical abortion.

Abortion pills RU-486 United Kingdom – Side Effects

Medical Abortions carried out with Mifeprex or RU486 are considered to be safe with rare and a very low number of complications. Common after effects post RU486 medications are: menstrual pain, bleeding and cramping. These are short-termed and go away soon. In case of persistent side-effects, one must immediately seek a doctor’s consultation.

 

Mifepristone is a synthetic steroid compound used as a pharmaceutical. It is used as an abortifacient in the first two months of pregnancy, and in smaller doses as an emergency contraceptive. During early trials, it was known as RU-486, its designation at the Roussel Uclaf company, which designed the drug. The drug was initially made available in France, and other countries then followed—often amid controversy. It is marketed under tradenames Mifegyne and Mifeprex.

Pharmacokinetics

Mifepristone is a progesterone antagonist with antiglucocorticoid activity. It binds to the intracellular progesterone receptor where it competitively inhibits progesterone attachment. It is also a partial progesterone agonist.

Absorption
Peak plasma concentrations after 1.3 hours.

Distribution
Protein-binding: 98%.

Metabolism
Hepatic: Undergoes first-pass metabolism.

Excretion
Faeces (as metabolites); urine (small amounts); 18 hours (ellimination half-life).

Mifepristone Adverse Reactions / Mifepristone Side Effects

Excessive vaginal bleeding; UTI; uterine haemorrhage; uterine infections; unusual tiredness or weakness; back pain; diarrhoea, nausea, vomiting; fever; dizziness; headache; anxiety; GI cramps.

Precautions

Warnings
Serious and sometimes fatal infections and bleeding occur very rarely following spontaneous, surgical, and medical abortions, including following mifepristone use.

Patients with serious bacterial infections and sepsis can present without fever, bacteremia or significant findings on pelvic examination following abortion. A high index of suspicion is needed to rule out sepsis.

Prolonged heavy bleeding may be a sign of incomplete abortion or other complications and prompt medical or surgical intervention may be needed. Advise patients to seek immediate medical attention if they experience prolonged heavy vaginal bleeding.

Advise patients to take their Medication Guide with them if they visit an emergency room or another health care provider who did not prescribe mifepristone, so that provider will be aware that patient is undergoing a medical abortion.

Monitor
Qualified health care provider must supervise administration. Clinical examination is necessary to confirm complete termination of pregnancy 14 days after mifepristone administration.

Emergency treatment
Adequate access to medical facilities equipped to provide emergency treatment of incomplete abortion, blood transfusions, and emergency resuscitation must be assured during period from first visit until discharged by health care provider.

Special Precautions

Asthma, COPD; women smokers >35 yr; CV disease or risk factors; smoking; alcoholism; prosthetic heart valve; history of infective endocarditis.

Other Drug Interactions

Decreased efficacy with aspirin and NSAIDs. Efficacy of corticosteroids (including inhaled) decreased, monitor patients during co-admin and for several days afterwards.

Dosage

Oral
Termination of pregnancy (49 days or less duration)
Adult: 600 mg as a single dose followed 2 days later by 400 mcg of misoprostol as single dose.

Oral
Postcoital contraception
Adult: 600 mg single dose within 72 hours of unprotected intercourse.

Oral
Termination of pregnancy up to 63 days
Adult: 600 mg as a single dose followed by 1 mg gemeprost vaginally after 36-48 hours.

Oral
Induction of labour following intrauterine fetal death
Adult: 600 mg daily for 2 consecutive days.

Oral
Termination of pregnancy between 13-24 weeks of gestation
Adult: 600 mg as a single dose given 36-48 hours prior to prostaglandin therapy.

Oral
Softening and dilatation of cervix prior to surgical termination of pregnancy
Adult: 600 mg as a single dose given 36-48 hours prior to the procedure.

Food(before/after)

May be taken with or without food. (Avoid grapefruit juice.)

List of Contraindications

Mifepristone and Pregnancy

Caution when used during pregnancy

Mifepristone and Lactation

Contraindicated in lactation

Mifepristone and Children

Safety and efficacy not established

Mifepristone and Other Contraindications

Confirmed or suspected ectopic pregnancy, chronic adrenal failure, concurrent long-term corticosteroid therapy, history of allergy to mifepristone, misoprostol or other prostaglandin, haemorrhagic disorders or concurrent anticoagulant therapy, porphyria, hepatic or renal impairment; pregnancy and lactation; IUD in place; undiagnosed adnexal mass.

Mifeprin kit
mifepristone and misoprostol
Weight 250.00 g

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